[The Cell Game] EBOOK / PDF


  • Hardcover
  • 432
  • The Cell Game
  • Alex PrudHomme
  • English
  • 13 February 2018
  • 9780060555566

Alex PrudHomme ✓ 0 Free download

characters ✓ PDF, DOC, TXT or eBook ✓ Alex PrudHomme The Cell Game Download Ç 100 Alex PrudHomme ✓ 0 Free download L and desperate to be liked entrepreneur Waksal was addicted to the trappings of wealth and fame that accrued to a darling of the stock market and the overheated atmosphere of biotech IPOs At the height of his stardom Waksal hobnobbed with Martha Stewart in New York and Carl Icahn in the Hamptons hosted parties at his fabulous art filled loft and was a fixture in the gossip columns He promised that Erbitux would change oncology and would soon be making 1 billion a yearBut as Waksal partied late into the night desperate cancer patients l. Compelling tale about greed and how the system worksThis is about the Cancer Game which might be seen as a part of the Cancer Industry a kind of bizarre and ghoulish phenomenon of modern times that exists precisely because there is no cure for cancer Indeed Alex Prud homme who is a gifted researcher and prose stylist whose work has appeared in such prestigious journals as The New Yorker Vanity Fair The New York Times etc might very well have called his book The Cancer Game I wonder why he didn t Would such a title have offended those who play the gameIt is specifically about the rise and fall of one Sam Waksal oldest son of Jewish emigrants and Holocaust survivors a man of irresistible charm fabulous energy and great intelligence a man driven to success and the high life a man who had bounced around academia without much success until in the 1980s he saw an opportunity to become a player in the cancer game and along with his younger brother Harlan founded ImClone Systems IncIt is also about an anticancer drug called Erbitux originally known as C225 because it was the 225th drug tested by its discoverers John Mendelsohn and Gordon Sato in 1980 It showed promise because in tests it stopped the growth of tumors in miceAnd finally it is a story about how drugs get discovered how they are developed and especially how they get approved or not by the Food and Drug Administration And of course it is about the Byzantine and incestuous relationship that exists between that August government agency and the massive pharmaceutical industryThe curious thing about all this is that Imclone never turned a profit Erbitux never came to market and most of the people associated with Waksal and ImClone either made out like bandits or got stuck holding the bag The drug itself which works against cancer tumors particularly colon cancer by cutting off the blood supply to the tumors an antiangiogenesis drug was touted as a miracle that would save the lives of innumerable patients and make possibly billions of dollars for ImCloneAt least this was the hype delivered by Sam Waksal and bought hook line and sinker by pharma giant Bristol Myers Suibb and by desperate cancer patients as well as salivating Wall Street investors who jumped on the bandwagon as ImClone s stock rocketed skyward Because of the promise of the drug Waksal himself was able to live his dream life as a New York socialite throwing lavish parties for celebs including Martha Stewart while he dated her daughter collecting fine art popping open 600 bottles of Chateau Lafite Rothschild while secretly selling stock on the side sending the proceeds overseas buying expensive apartments and houses for himself etc etcBut the cold hard facts of Erbitux like those of almost any cancer drug one can name are very far from the hype As Prud homme notes on pages 332 333 these agentsErbitux and others like Avastin and Iressa are remarkable scientific advances but they still only benefit some 10 to 20 percent of patients and they only extend patients lives by a matter of monthsThat s it That s the bottom line And yet these drugs are so valuable that the companies that end up selling them can make hundreds of millions if not billions of dollarsWaksal apparently came to this understanding sometime during the early eighties He realized first the simple fact that the way the cancer industry works is doctors have to prescribe something rather than nothing Then he realized that living a few months longer can mean a lot to people Therefore any FDA approved cancer drug will automatically fill a need What this means is that the PROMISE of a cancer drug if cleverly promoted will spark a rally in the shares of the company that owns the patent If like Sam Waksal you own millions of those shares you can get rich on mere promise aloneFurther should the drug have any real value at all and be approved or even look like it s going to be approved by the FDA you might be able to get some pharmaceutical giant like Bristol Myers Suibb to front a whole lot of money on that promise since they are desperate to find a cancer drug to replace those that have gone genericThis works because even drugs with very limited effectiveness are better than no drug at all This is true for many patients for many doctors and is especially true for the big pharmaceutical companiesNote that these drugs are valuable because the people who need them are typically people of relative means who can afford to pay large sums of money for them either through their HMOs their government or their own funds In contrast a drug that would prolong the life of poor people in third world countries would be of only marginal value to the big pharmaceutical companiesI should also mention that Prud homme spends some serious ink in this book on Waksal s long time friend Martha Stewart and her troubles Her personality her empire and the way she handles herself are vividly detailed In fact some readers might find her story the most interesting part of the book Dennis Littrell author of The World Is Not as We Think It Is

characters ✓ PDF, DOC, TXT or eBook ✓ Alex PrudHomme

The Cell Game

characters ✓ PDF, DOC, TXT or eBook ✓ Alex PrudHomme The Cell Game Download Ç 100 Alex PrudHomme ✓ 0 Free download Anguished waiting for his drug to come to market When the FDA withheld approval of Erbitux the charming scientist who had always stayed just one step ahead of bankruptcy panicked and desperately tried to cash in his stock before the bad news hit Wall StreetWaksal is now in jail the first of the Enron era white collar criminals to be sentenced Yet his cancer drug has proved durable than his evanescent profits Erbitux remains promising the leading example of a new way to fight cancer and patients and investors hope it will be available so. Great book to understand the biotech boom

Read & Download The Cell Game

characters ✓ PDF, DOC, TXT or eBook ✓ Alex PrudHomme The Cell Game Download Ç 100 Alex PrudHomme ✓ 0 Free download It began with a promising cancer drug the brainchild of a gifted researcher and grew into an insider trading scandal that ensnared one of America's most successful women The story of ImClone Systems and its miracle cancer drug Erbitux is the uintessential business saga of the late 1990s It's the story of big money and cutting edgescience celebrity greed and slipshod business practices; the story of biotech hype and hope and every kind of excessAt the center of it all stands a single enigmatic figure named Sam Waksal A brilliant mercuria. This book is like a biography of Imclone s co founder Sam Waksal a very charismatic person It describes his personal life with great details The author portrayed Sam Waksal as a habitual liar someone who is hungry for money and luxurious living who could easily attract people and used to get what he wanted of course until 2003 when he went to prison for insider trading and related chargesSam Waksal had been running Imclone for almost 20 years The fact that he managed to keep the company alive for so long without having a single product does indicate that he did has an extraordinary ualities People thought he was a great scientist with great social skills In late 2001 Imclone made headline news in USA by revealing its 2 billion deal with Bristol Myers Suibb to develop and commercialize cancer drug erbitux EGF R antagonist It was the largest deal in biotech world at that time However within next 2 years almost all of the Imclone s top executives were either in prison or no longer with the companyWhat happened Imclone s story is a classical example of corporate illusion After reading this book it becomes clear how easy it is to manipulate people and data Imclone s story reminds us about the disconnect between making science and making money posted by David Usharauli


6 thoughts on “[The Cell Game] EBOOK / PDF

  1. says: [The Cell Game] EBOOK / PDF

    [The Cell Game] EBOOK / PDF Read & Download The Cell Game This book is like a biography of Imclone's co founder Sam Waksal a very charismatic person It describes his personal life with great details The author portrayed Sam Waksal as a habitual liar someone who is hungry for money and luxurious living who could easily attract people and used to get what he wanted of course until 2003 when he went to prison for insider trading and related chargesSam Waksal had been running Imclone for alm

  2. says: Alex PrudHomme ✓ 0 Free download characters ✓ PDF, DOC, TXT or eBook ✓ Alex PrudHomme Read & Download The Cell Game

    [The Cell Game] EBOOK / PDF Compelling tale about greed and how the system worksThis is about the Cancer Game which might be seen as a part of the Cancer Industry a kind of bizarre and ghoulish phenomenon of modern times that exists precisely because there is no cure for cancer Indeed Alex Prud'homme who is a gifted researcher and prose stylist whose work has appeared

  3. says: [The Cell Game] EBOOK / PDF

    Read & Download The Cell Game characters ✓ PDF, DOC, TXT or eBook ✓ Alex PrudHomme Alex PrudHomme ✓ 0 Free download Great book to understand the biotech boom

  4. says: [The Cell Game] EBOOK / PDF

    [The Cell Game] EBOOK / PDF A fascinating book I was concerned that not traditionally having a great understanding of science the terminology would leave me in the dark however the explanations we're made uite well and I learned a lot not only about biogenics but also about the FDA and it's origins And I also learned about players like D

  5. says: [The Cell Game] EBOOK / PDF characters ✓ PDF, DOC, TXT or eBook ✓ Alex PrudHomme

    [The Cell Game] EBOOK / PDF First off I found this very well written It is rather long but I was captivated the entire time I would have given it stars except that it is already a bit dated I was hanging on every word and the book ended before the st

  6. says: [The Cell Game] EBOOK / PDF

    Read & Download The Cell Game Alex PrudHomme ✓ 0 Free download [The Cell Game] EBOOK / PDF Not really my type of book But I trudged my way through and finally finished it Interesting but a little too hea

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